Vahram Sargsyan studied composition with Ashot Zohrabyan at the Yerevan Komitas State Conservatory from 1998 to 2003, where he also studied choral conducting with Tigran Hekekyan from 2000 to 2006. He also studied composition at the Schulich School of Music, McGill University with composer Philippe Leroux.

Sargsyan's music has been performed in Armenia, UK, Germany, Austria, Belarus, Sweden, Lithuania, Latvia, Belgium, Russia, Greece, Poland, Italy, Japan, Canada, as well as in the United States. His composition Luis Zvart was performed at the 6th World Symposium on Choral Music (Minneapolis, Minnesota 2002). His arrangement of Khorurd Metz (Great Mystery) is included in the Oxford University Press anthology World Carols for Choirs (2005) and has been recorded by BBC Singers. It has been broadcast by BBC Radio 3.

He has had commissions from Oxford University Press (UK), A.R.CO.VA.(Italy), Boston Choral Ensemble (USA), Norddeutscher Rundfunk (Germany), AGBU Foundation (USA), CBC Radio and others. Sargsyan's work Hunting the Hunter was premiered under his own baton in 2012 at Carnegie Hall.

Vahram Sargsyan's name has appeared in Who is Who in Choral Music since 2007. He is a member of Composers' Union of Armenia. He served as a music consultant for European Choral Association - Europa Cantat from 2010 to 2012.

• Artiste de l’année à Laval (Quebec, Canada 2024)
• Jules Léger Prize for New Chamber Music . (Canada 2023, for Quiet Songs)
• The winner award in the POLYPHONOS 2017 Commission Competition (Seattle, USA 2016)
• Third prize in the Godfrey Ridout Awards from the Socan Foundation(2012, for Tribulationes);
• The winner award in the 3rd BCE Commission Competition (Boston, USA 2010, for Tribulationes)
• 1st prize in the International Contest for New Choral Compositions (Petrinja, Croatia 2009, for Anegh Bnutiun);
• An award from the World Armenian Congress “for creative achievements” (2009, for Mythis);
• Co-winner award at the European Seminar for Young Composers (Aosta, Italy 2008, for Laudate Dominum);
• An award in the Choral Composition Competition in Yerevan, Armenia (2006, for Tantum ergo).